JSPR Profile
Jasper Therapeutics, Inc. is a pioneering clinical-stage biotechnology company dedicated to advancing therapeutic agents for hematopoietic stem cell transplantation and gene therapies. The company specializes in developing and commercializing innovative conditioning agents and stem cell engineering technologies aimed at expanding the applications of stem cell transplantation and enhancing ex vivo gene therapy techniques. Ex vivo gene therapy involves the genetic manipulation of cells outside the body before their transplantation, a method Jasper Therapeutics is working to optimize and broaden.
The company’s flagship product candidate, JSP191, is a conditioning antibody currently in clinical development. JSP191 is designed to selectively clear hematopoietic stem cells from the bone marrow of patients undergoing allogeneic stem cell therapy or stem cell gene therapy. This selective depletion is crucial for improving the efficacy of subsequent stem cell transplantations and ensuring better outcomes for patients. Jasper Therapeutics is also focused on developing engineered hematopoietic stem cell product candidates, which aim to address and overcome the limitations associated with allogeneic and autologous gene-edited stem cell grafts.
Jasper Therapeutics’ research and development efforts are geared towards enhancing the precision and effectiveness of stem cell therapies, with the goal of providing more effective treatments for a range of hematologic and genetic disorders. By focusing on both the conditioning agents and the engineering of stem cells, the company is positioned at the forefront of innovation in the field, striving to improve patient outcomes and expand the therapeutic potential of stem cell-based treatments.
Headquartered in Redwood City, California, Jasper Therapeutics operates within a vibrant biotechnology ecosystem that supports cutting-edge research and development. The company’s strategic location and commitment to advancing stem cell and gene therapy technologies underscore its role as a key player in the evolution of personalized medicine and regenerative therapies.
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