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CRDL - Cardiol Therapeutics Inc.


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Cardiol Therapeutics Inc., a clinical-stage life sciences company, is dedicated to advancing innovative therapies targeting cardiovascular diseases (CVD) through its focus on anti-fibrotic and anti-inflammatory treatments. Based in Oakville, Canada, the company is pioneering research to develop therapies that address significant unmet medical needs in heart disease and related conditions. Its flagship product, CardiolRx, is a novel therapeutic under investigation for its potential to reduce cardiovascular and respiratory events in patients hospitalized with COVID-19. Currently, CardiolRx is undergoing a Phase II/III multinational, randomized, double-blind, and placebo-controlled clinical trial to assess its efficacy and safety as a cardioprotective agent in this context.

In addition to its COVID-19-related indications, CardiolRx is being evaluated for its potential benefits in acute myocarditis, an inflammation of the heart muscle that can lead to serious complications. This dual focus aims to leverage CardiolRx’s anti-inflammatory and anti-fibrotic properties to improve outcomes in patients with these severe conditions. The ongoing clinical trials are designed to provide critical data on the effectiveness of CardiolRx in reducing inflammation and fibrosis, which are key factors in the progression of heart disease.

Cardiol Therapeutics is also working on a subcutaneous formulation of CardiolRx, which is intended to address fibrosis and inflammation specifically related to heart failure. This formulation is part of the company’s broader strategy to provide more accessible and convenient treatment options for patients with chronic heart conditions. By focusing on fibrosis and inflammation, the company aims to offer new therapeutic options that could slow or potentially reverse the progression of heart failure.

Founded in 2017, Cardiol Therapeutics Inc. represents a new frontier in cardiovascular medicine with its innovative approach to treating complex heart diseases. The company's commitment to advancing its pipeline of therapies reflects its dedication to improving patient outcomes and addressing critical gaps in current treatment options. With its headquarters in Oakville, Canada, Cardiol Therapeutics continues to build on its research and development efforts to bring transformative therapies to market.

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